[
    {
        "id": "osp-12662",
        "type": "article-journal",
        "title": "Combined argon laser photocoagulation and antivascular endothelial growth factor for management of macular polypoidal choroidal vasculopathy",
        "author": [
            {
                "family": "Sen",
                "given": "Parveen"
            },
            {
                "family": "Kumar",
                "given": "S Vinay"
            },
            {
                "family": "Bhende",
                "given": "Muna"
            },
            {
                "family": "Sharma",
                "given": "Tarun"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/combined-argon-laser-photocoagulation-and-antivascular-endothelial-growth-factor-for-management-of-macular-polypoidal-choroidal-vasculopathy",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2016
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "9",
        "issue": "3",
        "page": "139-143",
        "DOI": "10.4103/0974-620x.192263",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Aim: To evaluate the efficacy of combination therapy of argon laser photocoagulation and intravitreal antivascular endothelial growth factor (VEGF) injection in idiopathic polypoidal choroidal vasculopathy (PCV) involving macula.\n\nMaterials and methods: A retrospective interventional study involving 12 eyes of 11 patients diagnosed with PCV involving the macula on indocyanine green angiography (ICGA). Intravitreal anti-VEGF was given in eyes with significant subretinal/sub retinal pigment epithelium hemorrhage or exudation. ICGA-guided focal laser was done to extrafoveal leaking polyps. Mean change in best-corrected visual acuity (BCVA) and regression of polyp as seen on ICGA were evaluated at the final follow-up.\n\nStatistical analysis: It was done using SPSS 17.0. - Mann-Whitney test.\n\nResults: 12 eyes of 11 patients underwent argon laser with intravitreal anti-VEGF injection. Ten patients were males and one female. Mean age was 65.75 ± 5.2 years. The mean number of injections given was 3.66 ± 1.5 (2-6) per eye. Mean number of laser sessions required was 1.33 ± 0.65 (1-3) per eye. BCVA improved in 25% (n = 3), remained stable in stable in 50% (n = 6) eyes, and decreased in 25% (n = 3) eyes. The regression of polypoidal lesions on ICGA was seen in 75% (n = 9) of eyes. Persistent subretinal fluid seen in 25% (n = 3) of eyes. The mean duration of follow-up was 15.41 ± 10.27 (3-36) months.\n\nConclusion: Combined argon laser photocoagulation with intravitreal anti-VEGF injection helps in decreasing exudation and results in stabilization of the disease with visual improvement in eyes with PCV involving macula."
    }
]