[
    {
        "id": "osp-10901",
        "type": "article-journal",
        "title": "Combination of Continuous Dexmedetomidine Infusion with Titrated Ultra-Low-Dose Propofol-Fentanyl for an Awake Craniotomy: Case report",
        "author": [
            {
                "family": "Das",
                "given": "Samaresh"
            },
            {
                "family": "Al-Mashani",
                "given": "Ali"
            },
            {
                "family": "Salhotra",
                "given": "Neelam"
            },
            {
                "family": "Neeraj",
                "given": ""
            },
            {
                "family": "Chatterjee",
                "given": "Nilay"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/combination-of-continuous-dexmedetomidine-infusion-with-titrated-ultra-low-dose-propofol-fentanyl-for-an-awake-craniotomy-case-report",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "16",
        "issue": "3",
        "page": "347-351",
        "DOI": "10.18295/squmj.2016.16.03.014",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "An awake craniotomy is a continuously evolving technique used for the resection of brain tumours from the eloquent cortex. We report a 29-year-old male patient who presented to the Khoula Hospital, Muscat, Oman, in 2016 with a two month history of headaches and convulsions due to a space-occupying brain lesion in close proximity with the left motor cortex. An awake craniotomy was conducted using a scalp block, continuous dexmedetomidine infusion and a titrated ultra-low-dose of propofol-fentanyl. The patient remained comfortable throughout the procedure and the intraoperative neuropsychological tests, brain mapping and tumour resection were successful. This case report suggests that dexmedetomidine in combination with titrated ultra-low-dose propofolfentanyl are effective options during an awake craniotomy, ensuring optimum sedation, minimal disinhibition and a rapid recovery. To the best of the authors’ knowledge, this is the first awake craniotomy conducted successfully in Oman."
    }
]