[
    {
        "id": "osp-12942",
        "type": "article-journal",
        "title": "Clinicopathological correlation of choroidal melanoma in Indian population: A study of 113 cases",
        "author": [
            {
                "family": "Dhupper",
                "given": "Maneesh"
            },
            {
                "family": "Biswas",
                "given": "Jyotirmay"
            },
            {
                "family": "Gopal",
                "given": "Lingam"
            },
            {
                "family": "Kumar",
                "given": "S Krishna"
            },
            {
                "family": "Khetan",
                "given": "Vikas"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/clinicopathological-correlation-of-choroidal-melanoma-in-indian-population-a-study-of-113-cases",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2012
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "5",
        "issue": "1",
        "page": "42-45",
        "DOI": "10.4103/0974-620x.94766",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Aim: To correlate the clinical presentation, tumor characteristics, and histopathological findings of choroidal melanoma in the Indian population\n\nMaterials and methods: A retrospective analysis of 113 patients of choroidal melanoma over a period of 10 years was done. Patient demography, clinical presentation, tumor characteristics, and histopathological findings were correlated.\n\nResults: Among 113 patients histopathologically diagnosed with choroidal melanoma over 10 years, most were males. The mean age was 45.9 ± 14.84 years among which 6 (5.3%) patients were less than 20 years. Thirty-six (31.8%) patients were misdiagnosed. The mean basal diameter was 12.41 ± 1.4 mm. Mixed cell type was seen in 71 (63%) patients, while 28 (25%) patients had spindle cell type. Epithelioid cell type was present in 11 (10%) patients and necrotic cell type was seen in 3 (2%) patients. Enucleation was the primary treatment modality in 107 (94.6%) patients, while exenteration was done in 6 (5.3%) patients. Three patients with epithelioid cell type with orbital extension underwent exenteration. The mean follow-up period was 14 months. No mortality was reported at the end of 5 years in patients with longer follow-up.\n\nConclusions: Malignant melanoma of the choroid is a rare occurrence. They can occur in younger age group and can be misdiagnosed. Mixed cell type is commonest. Diffuse tumors with epithelioid cell type are likely to have orbital extension."
    }
]