[
    {
        "id": "osp-11776",
        "type": "article-journal",
        "title": "Are Scintigraphy and Ultrasonography Necessary Before Fine-Needle Aspiration Cytology for Thyroid Nodules?",
        "author": [
            {
                "family": "Sankhla",
                "given": "Dilip K."
            },
            {
                "family": "Hussein",
                "given": "Samir S."
            },
            {
                "family": "El Shafie",
                "given": "Haddia"
            },
            {
                "family": "Omeima",
                "given": ""
            },
            {
                "family": "Woodhouse",
                "given": "Nicholas J."
            },
            {
                "family": "Nirmala",
                "given": "V"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/are-scintigraphy-and-ultrasonography-necessary-before-fine-needle-aspiration-cytology-for-thyroid-nodules",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "3",
        "issue": "1",
        "page": "29-33",
        "DOI": "10.18295/2075-0528.2576",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objective: To evaluate the effi cacy of scintigraphy, ultrasound and fi ne-needle aspiration in thyroid nodules and to establish the best diagnostic pathway in detecting thyroid cancer. Method: Two hundred and sixteen patients with thyroid nodules were examined using high-resolution ultrasonography, 99mTc thyroid scintigraphy and ultrasound-guided fi ne-needle aspiration. Of these, 113 patients subsequently underwent thyroidectomy. The remaining 103 were followed up for two years without any evidence of malignancy. Results: Cytopathology classifi ed 71% of the aspirate as benign, 3% as positive for malignancy, 21% as suspected neoplasia and 5% as unsatisfactory. Fine- needle aspiration cytology had a sensitivity of 87.5% and specifi city of 80%. On ultrasound 33% of malignant nodules were hypo-echoic and on scintigraphy 16% of solitary cold nodules were malignant. Neither test could reliably diagnose thyroid cancer. conclusion: Ultrasound-guided fi ne-needle aspiration cytology should be the fi rst test performed in euthyroid patients with a thyroid nodule. Scintigraphy and ultrasound imaging should be reserved for follow-up studies and patients who have suppressed levels of thyroid stimulating hormone."
    }
]